Frau Weitergelesen hat eines, die Hilli auch und sogar Crosa. Und ich will auch eines! So ein Bildchen!
Wenn ich bei anderen kommentiere, die Gravatare nutzen in ihren Kommentaren, bin ich immer ein Strichmännchen oder bunte Muster. Doch ich will auch ein Bildchen sein!!! *quengelig mit dem Fuß aufstampf*
Wie macht man das denn? Seid doch so lieb und gebt euer Geheimnis an die arme, bilderlose kleine Fudge weiter!!! Biiiiiiiitte!!!
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Bulevirtide, bought under the model identify Hepcludex, is
an antiviral medication for the remedy of chronic hepatitis
D (within the presence of hepatitis B). The most common unwanted effects embody raised levels
of bile salts within the blood and reactions at the location of
injection. Bulevirtide works by attaching to and blocking a receptor (goal) by means of which the hepatitis delta and hepatitis B viruses enter liver cells.
By blocking the entry of the virus into the cells, it limits the ability of HDV to replicate and
its results within the physique, lowering symptoms of the disease.
Bulevirtide is indicated for the remedy of chronic hepatitis delta virus (HDV) infection in plasma (or serum) HDV-RNA optimistic adult patients with compensated liver illness.
Bulevirtide binds and inactivates the sodium/bile acid cotransporter, blocking each viruses from getting into hepatocytes.
The hepatitis B virus makes use of its surface lipopeptide pre-S1 for docking to mature liver cells through their sodium/bile acid
cotransporter (NTCP) and subsequently getting into the cells.
NTCP, blocking the virus’s entry mechanism. The drug can be effective in opposition to
hepatitis D because the hepatitis D virus is barely effective
in the presence of a hepatitis B virus infection. Deterding, Ok.; Wedemeyer, H.
(2019). “Past Pegylated Interferon-Alpha: New Remedies for Hepatitis Delta”.
AIDS Opinions. 21 (3): 126-134. doi:10.24875/AIDSRev.19000080.
European Medicines Company (EMA). 26 May 2020. Retrieved 12 August 2020.
Text was copied from this source which is © European Medicines Agency.
Reproduction is authorized supplied the supply is acknowledged.
Sauter M, Blank A, Stoll F, Lutz N, Haefeli WE, Burhenne J (Could 2021).
“Intact plasma quantification of the large therapeutic lipopeptide bulevirtide”.
Analytical and Bioanalytical Chemistry. PDF). European Medicines Company.
Francisco, Estela Miranda (29 Might 2020). “Hepcludex”.
Volz T, Allweiss L, Ben MBarek M, Warlich M, Lohse AW, Pollok JM, et al.
Might 2013). “The entry inhibitor Myrcludex-B effectively blocks intrahepatic virus spreading in humanized mice beforehand contaminated with hepatitis B virus”.
Abbas Z, Abbas M (August 2015). “Administration of hepatitis delta: Need for novel therapeutic choices”.
World Journal of Gastroenterology. 21 (32): 9461-5. doi:10.3748/wjg.v21.i32.9461.
Spreitzer H (14 September 2015). “Neue Wirkstoffe – Myrcludex B”.
Drug Data Portal. U.S. National Library of Medication. This antiinfective drug article
is a stub. You can assist Wikipedia by increasing it. This page was final edited on 9 December 2022, at 01:
Forty four (UTC). Textual content is offered beneath the Creative Commons Attribution-ShareAlike License 3.0; extra phrases could apply.
Through the use of this site, you comply with the Terms of Use and Privateness Policy.
Wikipedia® is a registered trademark of the Wikimedia Foundation,
Inc., a non-revenue organization.
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